Chief Ironside has just retired and is looking forward to running his vineyard with his wife. But his retirement is interrupted when his old friend and colleague Ed Brown, who is now working for the Denver police department comes to him and asks him to fill in the vacancy left by the untimely death of the Chief. Ironside does so but with condition that it will only be temporary. But things are further complicated when Suzanne Dwyer the daughter of his old friend and colleague, Eve Whitfield is the prime suspect in the murder of her boyfriend, Mike Quinn, whom she suspected was seeing someone else. Though Ironside refuses to believe that Suzanne is guilty; the evidence is all against her. So, Ironside's other old friends, Mark Sanger and Fran Belding come to Denver to help. It also seems that this whole matter could be connected with previous Chief's (death) murder, and also seems that someone in the department is responsible.