After an assignment in Tokyo, the dangerous CIA assassin Avery "Ave" Graves returns home in Croatia to celebrate her marriage anniversary with her beloved husband David Brooks. Ave is a lonely woman that was raised to be a CIA operative since she was a teenager by her chief and friend Jarvis Hedlund, the only person she trusts besides David. Out of the blue, David is kidnapped, and the kidnapper orders her to retrieve the Canary Black file that is hidden in the tooth of a CIA prisoner. She lures Agent Maxfield, who is responsible for the prisoner, but she does not find any file in the tooth. Now she is chased by the CIA that believe she is a traitor and has the Black Canary file; by the criminals who abducted David, since they also believe she has the file; and the Croatia Secret Service that has team up with the CIA to capture her. Meanwhile the clock is ticking, and David's life is in serious danger, and Ave needs to retrieve the Black Canary to save him.